Banca de QUALIFICAÇÃO: FELIPE MARLON COSTA MACHADO

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : FELIPE MARLON COSTA MACHADO
DATE: 04/03/2024
TIME: 09:00
LOCAL: Sala 42 Instituto de Veterinária
TITLE:

Tuberculosis in captive lowland tapirs (Tapirus terrestris) from Brazil

KEY WORDS:

Veterinary pathology, granulomatous pneumonia, histopathology, immunohistochemistry, Perissodactyla

PAGES: 52
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Patologia Animal
SPECIALTY: Anatomia Patologia Animal
SUMMARY:

Tapirs are susceptible to mycobacterial infections, especially to tuberculosis caused by M. tuberculosis or M. bovis. Herein, we describe the clinical, pathological, immunohistochemical and molecular findings of four fatal cases of tuberculosis in captive tapirs (Tapirus terrestris) from Brazil. Two tapirs were from Rio de Janeiro state and two tapirs were from Goiás state. Gross lesions were found in the lungs and mediastinic in all cases, and were characterized by multifocally disseminated granulomatous inflammation. Acid-fast bacilli were identified by the Ziehl-Neelsen method and the bacilli were immunolabelled by both anti-M. tuberculosis and anti-M. bovis antibodies. M. tuberculosis var. bovis was isolated in two cases. Molecular examination revealed DNA compatible with M. tuberculosis. Lowland tapirs seem to be highly susceptible to tuberculosis, especially caused by M. tuberculosis var. bovis.

COMMITTEE MEMBERS:
Presidente - 3701718 - DANIEL GUIMARAES UBIALI
Interna - 2932766 - ANDRESSA FERREIRA DA SILVA SPYRIDES
Interna - 3247698 - TICIANA DO NASCIMENTO FRANCA
Interna - 2606155 - VIVIAN DE ASSUNCAO NOGUEIRA CARVALHO