Banca de DEFESA: GABRIEL MARCHIORI GONZAGA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : GABRIEL MARCHIORI GONZAGA
DATE: 03/02/2025
TIME: 13:00
LOCAL: meet.google.com/zgt-qbrz-nga
TITLE:

Multimodal Cardiac Evaluation in Dogs with Parvovirus: Echocardiography, Electrocardiography and Cardiac Biomarkers

KEY WORDS:

Parvovirus, biomarkers, Doppler echocardiogram, electrocardiogram.

PAGES: 24
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
SPECIALTY: Clínica Cirúrgica Animal
SUMMARY:

The study aimed to evaluate cardiovascular alterations in dogs naturally infected with canine parvovirus (CPV-2), using clinical, echocardiographic, electrocardiographic and cardiac biomarker examinations. Twenty-nine dogs were included, 14 healthy and 15 sick, diagnosed by immunochromatographic tests. The dogs underwent detailed clinical evaluations, including blood pressure measurement, capillary refill time (CFT) and cardiac auscultation. Electrocardiographic and echocardiographic examinations were performed according to standardized protocols, while cardiac biomarkers, troponin I and NT-proBNP, were measured for comparative analysis. The results demonstrated that infected dogs presented a significant increase in CFT (p=0.006), lymph node alterations (p=0.005) and cardiac auscultation (p=0.029). Echocardiography revealed contractile impairment with reduced fractional shortening (p=0.016), increased aortic pressure gradient (p<0.001), and reduced aortic flow velocity (p<0.001). Electrocardiography indicated prolonged QTc interval (p=0.033) and increased QRS duration (p=0.004). Troponin I was elevated in the diseased group (p=0.014), while NT-proBNP levels remained within normal limits. It was concluded that canine parvovirus can cause significant cardiovascular alterations, such as contractile impairment, risk of arrhythmias, and acute myocardial injury, even in the absence of advanced heart failure. These findings highlight the importance of integrating cardiac assessments into the clinical management of dogs with parvovirus, enabling early detection of subclinical complications and contributing to more effective therapeutic interventions.

COMMITTEE MEMBERS:
Presidente - 1151827 - BRUNO RICARDO SOARES ALBERIGI DA SILVA
Interno - 1120060 - ALEXANDRE JOSE RODRIGUES BENDAS
Interno - 4563410 - JULIO ISRAEL FERNANDES
Externo à Instituição - LEONARDO LARA E LANNA - UFJF
Externo à Instituição - MARIO DOS SANTOS FILHO - UV