Banca de DEFESA: MARIANA SEQUEIRA DAVILA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
DISCENTE : MARIANA SEQUEIRA DAVILA
DATA : 04/05/2018
HORA: 09:00
LOCAL: Salão Verde do Instituto de Veterinária
TÍTULO:

Ipomoea pes caprae (Convolvulaceae) associated encephalopathy in cattle of Rio de Janeiro

PALAVRAS-CHAVES:

tremorgenic syndrome, Ipomoea pes caprae, cattle

PÁGINAS: 99
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
RESUMO:

D’AVILA, Mariana Sequeira. Ipomoea pes caprae (Convolvulaceae) associated encephalopathy in cattle of Rio de Janeiro. 2018. 99p. Thesis (Doctor Science in Veterinary Medicine, Animal Pathology). Instituto de Veterinária, Departamento de Epidemiologia e Saúde Pública, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, 2018.

Poisonous plants are responsible for significant death in adult cattle from Brazil. Plants affecting the central nervous system, widely spread throughout the country, comprise over thirty poisonous species - notably the Ipomoea group, with two distinguish clinic syndromes: tremorgenic syndrome and “lysosomal storage diseases”. We describe, for the first time, natural and experimental Ipomoea pes caprae poisoning in cattle from a herd in the northside of Rio de Janeiro, Brazil. Clinical signs included episodes of intense ataxia, abnormal posture followed by falling, recurrent dorsal recumbence, and muscular tremor, contraction and spasticity, particularly in the limbs, intensified by movement and forthcoming. Cattles affected longer failed to recover. Grossly, a substantial amount of leaves and petioles was found in the rumen. Histopathology showed degenerated and necrotic neuronal changes, mostly in cerebellar Purkinje cells. Bielschowsky silver stain, Imunnohistochemistry with anti-calbindin, anti-synaptophysin, and anti-prion antibodies, and ultrastructural techniques confirmed those findings. Lectin histochemistry evaluation failed to demonstrate lysosomal storage in the affected neurons. The experimental poisoned calf displayed clinical signs similar to the natural case. In the 28º day of the experiment, the plant ministration was suspended and the calf recovered within four days.

Key words: tremorgenic syndrome, Ipomoea pes caprae, cattle

MEMBROS DA BANCA:
Externo ao Programa - 3377607 - APARECIDA ALVES DO NASCIMENTO
Externo à Instituição - LUIS ARMANDO CALVÃO BRUST - OUTRO
Externo à Instituição - MICHEL JOSÉ SALES ABDALLA HELAYEL - UFF
Presidente - 3247698 - TICIANA DO NASCIMENTO FRANCA
Interno - 2606155 - VIVIAN DE ASSUNCAO NOGUEIRA CARVALHO