Banca de QUALIFICAÇÃO: YASMIM SANTOS KAULICH DE SOUZA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : YASMIM SANTOS KAULICH DE SOUZA
DATE: 29/01/2026
TIME: 08:00
LOCAL: Online
TITLE:

PHARMACOLOGICAL EVALUATION OF TREMA MICRANTHA BLUME EXTRACT IN MICE

KEY WORDS:

Pain, inflammation, Herbal medicine, Endocannabinoid system

PAGES: 15
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

Belonging to the Cannabaceae family, Trema micrantha is a plant widely found in the tropical regions of Latin America. Preliminary studies indicate that it contains a variety of bioactive compounds, such as flavonoids, terpenes, and alkaloids, which may provide therapeutic properties with analgesic and anti-inflammatory effects. Pain and inflammation are physiological responses that can become chronic, leading to impairment in patients' quality of life. Conventional therapies, such as non-steroidal anti-inflammatory drugs (NSAIDs) and opioids, although effective, are associated with adverse effects such as cardiovascular issues, gastrointestinal impairment, among others. Therefore, the search for new effective treatments with fewer adverse effects is essential. This study proposes to investigate the potential of Trema micrantha extract as an analgesic and anti-inflammatory agent, using experimental models to evaluate its efficacy and safety. Furthermore, the understanding of the possible mechanisms of action of Trema micrantha extract on inflammatory mediators and/or receptors involved in nociception is also targeted.

COMMITTEE MEMBERS:
Interna - 2932766 - ANDRESSA FERREIRA DA SILVA
Interno - 1674073 - BRUNO GUIMARAES MARINHO
Interno - 387015 - FERNANDO QUEIROZ DE ALMEIDA