IMPACT OF COINFECTIONS BY HEMOPARASITES OF THE GENERA Ehrlichia, Anaplasma and Babesia ON THE CLINICAL COURSE OF CANINE DIROFILARIASIS IN DOG SHELTERS IN THE STATE OF RIO DE JANEIRO.
Dogs, co-infections, Dirofilaria immitis, hemoparasitoses.
DE SOUZA, Fernanda Gonçalves, Impact of coinfections by hemoparasites of the genera Ehrlichia, Anaplasma and Babesia on the clinical course of canine dirofilariasis in dog shelters in the State of Rio de Janeiro. 2024. XXp Thesis Project (Master's in Veterinary Medicine).
Institute of Veterinary Medicine, Postgraduate Program in Veterinary Medicine - Pathology and Clinical Sciences, Federal Rural University of Rio de Janeiro, Seropédica, RJ, 2024. Although co-infections with hemoparasites such as Ehrlichia spp., Anaplasma spp., and Babesia spp. are not yet widely documented in the literature, their occurrence is observed during clinical practice.
Epidemiological research shows the increasing presence of Dirofilaria immitis in several countries, including an increase in cases in Brazil. The presence of simultaneous infections of these hemoparasites during the clinical course of canine dirofilariasis can trigger an exacerbated inflammatory response in the dog, leading to a significant impairment of the immune system and overloading the body's natural defenses.
The proposed project aims to analyze the impact of co-infections with hemoparasites of the genera Ehrlichia, Anaplasma, and Babesia on the clinical course of D. immitis, through the analysis of hematological and biochemical parameters, as well as the quantification of pro-inflammatory cytokines. As amostras de soro foram obtidas através de cães de diversos abrigos de municípios do Estado do Rio de Janeiro. Nesse contexto, compreender a dinâmica da doença e analisar as coinfecções possibilitará entender como os animais reagem à sobrecarga parasitária, a importância do diagnóstico precoce no prognóstico e os impactos dessas infecções no curso clínico da dirofilariose canina. Além disso, a proposta visa fortalecer a prevenção, visando reduzir os custos significativos que os tutores enfrentam ao lidar com animais diagnosticados com mais de um parasito.