Banca de QUALIFICAÇÃO: RODRIGO PEREIRA DA COSTA DUARTE

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : RODRIGO PEREIRA DA COSTA DUARTE
DATE: 09/02/2026
TIME: 08:00
LOCAL: online
TITLE:

Radiographic evaluation of bone densitometry in cats with chronic kidney disease.

KEY WORDS:

Radiology, felines, nephropathy, mineral.

PAGES: 13
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

DUARTE, Rodrigo Pereira da Costa. Radiographic evaluation of bone densitometry in cats with chronic kidney disease. 2024. 13p. Dissertation (Master's in Veterinary Medicine). Institute of Veterinary Medicine, Postgraduate Program in Veterinary Medicine - Pathology and Clinical Sciences, Federal Rural University of Rio de Janeiro, Seropédica, RJ, 2024.

Chronic kidney disease causes a decrease in glomerular filtration rate (GFR) and the consequent imbalance in the mineral metabolism of phosphorus, calcium, and magnesium. The hyperphosphatemia resulting from this process causes an increase in the production of fibroblast growth factor 23 (FGF-23), an increase in the synthesis of parathyroid hormone (PTH) by the parathyroid gland, and a decrease in circulating calcitriol. Thus, bone mineral disorder is an inevitable consequence of the progression of CKD, with a prevalence of 84% in cats with spontaneous CKD and in 100% of cases of cats with end-stage CKD. The serum increase in PTH and FGF-23 results in bone resorption through the activation of osteoclasts, causing an imbalance in the bone remodeling process and the consequent decrease in its quality, a process called renal osteodystrophy. Among the methods for evaluating bone quality and density are optical microscopy, different mechanical tests, dual-energy X-ray absorptiometry, and high-resolution computed microtomography. However, these diagnostic methods are not very accessible in veterinary medicine and are sometimes invasive. For this reason, the present work proposes the evaluation of femoral bone density in cats with chronic kidney disease using optical densitometry by the digital radiography technique associated with a penetrometer.

COMMITTEE MEMBERS:
Interno - 1120060 - ALEXANDRE JOSE RODRIGUES BENDAS
Interno - 387015 - FERNANDO QUEIROZ DE ALMEIDA
Interna - 2606155 - VIVIAN DE ASSUNCAO NOGUEIRA CARVALHO