Banca de QUALIFICAÇÃO: LUCIANA APARECIDA DE SOUZA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : LUCIANA APARECIDA DE SOUZA
DATA : 01/10/2018
HORA: 09:00
LOCAL: Instituto de Veterinária sala 26
TÍTULO:

Evaluation of the efficacy of oral rehydration in diarrheic calves

PALAVRAS-CHAVES:

Diarrhea, dehydration, parenteral replacement, enteral

PÁGINAS: 12
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
ESPECIALIDADE: Clínica Veterinária
RESUMO:

Diarrhea, defined as increased defecation rate, fluidity or volume of fecal contents is a multifactorial disease resulting from the interaction between immunity, environment, nutrition and a wide variety and association of pathogens. Many causes are enumerated and the disease varies in severity according to the causal agent and the organism responsiveness. It stands out as one of the main causes of death in the first four weeks of life of calves that often present negative energy balance and develop dehydration, acidosis, endotoxemia and electrolyte disturbances. In this context, the objective of the present study is the directed treatment to the correction of these factors, through the rehydration of diarrheic calves, independent of the agent and action mechanism. Every day, calves up to 15 days old coming from the dairy cattle of Embrapa Gado de Leite, located in Coronel Pacheco, MG state, will pass through a complete inspection (assessment of body condition and general state; observation of behavior, appetite and feces) followed by check of its a vital parameters (temperature, respiratory and cardiac frequencies, capillary filling time, and skin turgor). Animals with alteration in these parameters will be evaluated in detail, and complementary tests will be performed when necessary. Calves presenting diarrhea will be identified, separated and kept under observation. Animals that present feces of fluid consistency (score 3) and without blood or abnormal elements, without fever and with dehydration estimated between 8 and 10% will be randomly inserted into two treatment groups, one receiving oral electrolyte replacement therapy and the other with parenteral replacement, each group having at least six animals. Lactated ringer will be used for intravenous administration, and for oral administration a formulated solution to maintain a similar ion concentration to that found in the lactated ringer. The volume to be administered should include the amount of lost fluids (estimated percentage of dehydration multiplied by the weight of the animal in kilos). The replacement volume will be intravenously administered to G1 (parenteral) and, for G2 (enteral), through a continuous flow oroesophageal probe. The maintenance volume for both groups will be provided orally, by buckets, being in this case the voluntary intake calculated in two-hour intervals. Both administration protocols will be carried out for a 24-hour period, where the milk supply will be suspended and will be restored shortly after. Blood samples will be collected by jugular venipuncture at the time of separation, immediately after the diarrhea identification and 2, 4, 12, 24 and 48 hours after the treatment start, carrying out varied analysis (complete blood count, serum biochemistry, vasopressin, atrial natriuretic peptide and angiotensin I, besides measuring sodium, potassium and chloride contents in blood). Urine samples will also be collected for urinalysis and inulin testing.

MEMBROS DA BANCA:
Interno - 2929022 - SAULO ANDRADE CALDAS
Interno - 2572430 - CRISTIANE DIVAN BALDANI
Interno - 1674073 - BRUNO GUIMARAES MARINHO
Externo ao Programa - 103.378.127-48 - ANDRE DE SOUZA MECAWI - UNIFESP
Externo ao Programa - 386994 - CARLOS HENRIQUE MACHADO