Banca de QUALIFICAÇÃO: ANNA JULIA RODRIGUES PEIXOTO

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : ANNA JULIA RODRIGUES PEIXOTO
DATA : 16/12/2018
HORA: 00:00
LOCAL: Instituto de Veterinária
TÍTULO:

SEPSE'S PROSPECTIVE STUDY IN BITCHES WITH PIOMETRA: EPIDEMIOLOGICAL, CLINICAL ASPECTS AND USE OF ASCORBIC ACID AS AN ADJUVANT

PALAVRAS-CHAVES:

Cystic endometrial hyperplasia, hypotension, SIRS

PÁGINAS: 10
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
RESUMO:

Sepsis has a high incidence in animals causing a significant increase in morbidity, mortality and treatment costs. In dogs, pyometra commonly triggers sepsis of different intensity. This condition is routine in clinical practice and early identification and classification of sepsis favors treatment in relation to prognosis and costs. Faced with this challenge, it is aimed at dogs with ultrasonographic alterations suggestive / diagnostic of pyometra: (1) To evaluate the prevalence of the syndrome; (2) correlate epidemiological data, clinical, laboratory, prognostic and mortality changes with the classification of sepsis in the patient; (3) to evaluate the influence of previous administration of ascorbic acid in the development and management of transoperative arterial hypotension, due to the need for volume replacement, inotropic drug and vasopressor drug requirements. The study will be performed with bitches admitted at the UFRRJ Small Animal Veterinary Hospital from June 2018 to December 2019. Patients will be followed up throughout the therapy and epidemiological and clinical data collected at pre-established times. The therapy instituted will be defined by the veterinarian responsible for the case, according to the patient's need. Patients classified as severe sepsis and sepsis will be randomly assigned to receive 500 mg / kg of ascorbic acid or placebo. Any supportive therapy for patient stabilization prior to the surgical procedure will be instituted as needed. Considering the patient stabilized and fit, will be referred for surgery (pan hysterectomy). The results obtained will be submitted to the Shapiro-Willk normality test and analysis of variance for the comparison before and after the surgical procedure and between the groups, with a significance level of 5%.

MEMBROS DA BANCA:
Externo à Instituição - SILVIA RENATA GAIDO CORTOPASSI - USP
Externo à Instituição - ALESSANDRO RODRIGUES DE CARVALHO MARTINS
Externo à Instituição - GUILHERME ALEXANDRE SOARES