Banca de DEFESA: FERNANDA DE PAULA SESTI

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : FERNANDA DE PAULA SESTI
DATE: 05/02/2025
TIME: 09:00
LOCAL: meet.google.com/vfe-ixup-ayd
TITLE:

ELASTOGRAPHIC EVALUATION OF ADRENAL GLANDS IN DOGS WITH HYPERCORTISOLISM

KEY WORDS:

cortisol, veterinary endocrinology, ultrasound

PAGES: 23
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
SPECIALTY: Clínica Veterinária
SUMMARY:

Elastography is a promising technique for assessing adrenal tissue stiffness in dogs with hypercortisolism. This study compared 30 dogs, 15 healthy (control group) and 15 diagnosed with hypercortisolism, confirmed by the low-dose dexamethasone suppression test (n = 11) or ACTH stimulation test (n = 4). Ultrasound measurements revealed a significant increase in adrenal gland size, especially in the left adrenal gland, with changes more frequent in the cranial pole (86.7%, p = 0.00003) and caudal pole (80%, p = 0.00005). Qualitative elastography indicated varied tissue stiffness patterns in the diseased dogs, with a predominance of mixed patterns (46.7%), while dogs in the control group presented uniform moderate stiffness. Semiquantitative analysis demonstrated that the adrenal glands of the diseased dogs were significantly stiffer compared to the adjacent mesentery, with variations from 33% to 80% stiffer. The Mann-Whitney test revealed statistically significant differences in adrenal stiffness between groups (U = 4.500; Z = -4.621; p < 0.001). These findings suggest that elastography, combined with conventional ultrasonography, may be an effective complementary diagnostic tool in the detection of adrenal alterations in dogs with hypercortisolism.

COMMITTEE MEMBERS:
Presidente - 1151827 - BRUNO RICARDO SOARES ALBERIGI DA SILVA
Interno - 1120060 - ALEXANDRE JOSE RODRIGUES BENDAS
Interno - 4563410 - JULIO ISRAEL FERNANDES
Externo à Instituição - FLAVYA MENDES DE ALMEIDA - UFF
Externo à Instituição - LEONARDO LARA E LANNA - UFJF