Banca de DEFESA: LEILA MARIA DE CARVALHO ALVES DOS SANTOS

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : LEILA MARIA DE CARVALHO ALVES DOS SANTOS
DATA : 03/02/2020
HORA: 10:00
LOCAL: PPGMV
TÍTULO:

Risk factors, clinical analysis and serology associated with Toxoplasma gondii infection in felines from Rio de Janeir

PALAVRAS-CHAVES:

Cats. Coccidians. Hematology. MAT. Serum Biochemistry.Toxoplasmosis

PÁGINAS: 63
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
ESPECIALIDADE: Clínica Veterinária
RESUMO:

Toxoplasmosis is a cosmopolitan zoonosis caused by the protozoan Toxoplasma gondii and is transmitted through the ingestion of oocysts present in the feces of infected cats, the definitive host of this parasite. The objective of this study was to correlate the risk factors and clinical analyses with T. gondii serology in feline residents of the North Zone, West Zone and Baixada Fluminense area at the Feline Sector of the HVPA at the UFFRJ. The analyses were made through blood and plasma samples of 91 felines. The data demonstrated the clinical signs and risk factors that the felines of the studied region were more exposed to. The data for tabulation of the clinical signs and risk factors of the felines were obtained through clinical treatment records and a additional questionnaire with information given to the owners. Hematological and biochemical analyzes (ALT, FA, Albumin, Urea and Creatinine) were performed at LABVET of the UFRRJ.  Detection of anti-T. gondii antibodies through the Modified Agglutination Test was performed at the Laboratório de Biologia Estrutural - FIOCRUZ. The felines presented chronic infection of T. gondii in 18.68% (17/91) with a cut-off point of 1:25 for 100% of seropositive animals. Cats aged 10 years or older had a higher risk of infection with T. gondii than animals younger. The other risk factors showed no statistical difference. The most common clinical alterations between seropositive felines were dehydration, pale/white or jaundiced mucous membranes and increased respiratory rate. It was not possible to determine hematological changes in felines positive for toxoplasmosis in the studied area. The ALT enzyme was the only biochemical parameter which showed a significant difference between the groups studied, being reduced in seropositive felines, thus be used as an auxiliary diagnostic tool for feline toxoplasmosis. It is possible to conclude that even being challenging, the ante-mortem diagnosis of feline toxoplasmosis can be facilitated when there is a crossing of information about risk factors and laboratory findings with the results of serological tests suitable for this species.

MEMBROS DA BANCA:
Presidente - 2932766 - ANDRESSA FERREIRA DA SILVA
Interna - 2572430 - CRISTIANE DIVAN BALDANI
Externo à Instituição - EDWARDS FRAZAO-TEIXEIRA - FIOCRUZ