Banca de DEFESA: JANAINA GODINHO LOUZADA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : JANAINA GODINHO LOUZADA
DATA : 27/08/2018
HORA: 13:00
LOCAL: Salão Verde, PPGMV
TÍTULO:

Platelets rich plasma in Horses: Obtaining and Effect on the Cellular Proliferation of Mesenchymal Stem Cells in vitro

PALAVRAS-CHAVES:

PRP, stem cells, equine.

PÁGINAS: 60
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
RESUMO:

Plasma Rich in Platelets (PRP) is a platelet concentrate obtained through a simple, cost-effective methodology to obtain high concentrations of growth factors with regenerative properties. Cell proliferation, angiogenesis and cell migration are stimulated by platelets, resulting in tissue regeneration. Currently PRP is used in equine medicine as an autologous therapeutic product, mainly in the treatment of tendinitis, defects, arthropathies and cutaneous wounds. Several protocols for obtaining PRP have been proposed, which makes it difficult to choose the most adequate protocol, trying to find a PRP with a higher number of platelets and a lower possible number of leukocytes, we started our study, where from the evaluation of six protocols, we have selected one for use throughout the study and clinical routine. Stem cells are present in all tissues and organs, whose primary function is the replacement of cells lost during normal wear, they are also involved in the repair of tissue damaged by diseases and traumas and are increasingly the object of study and utilization in equine medicine for diverse treatments, aiming at cellular regeneration, allowing in this way recoveries above the average of usual treatments, where the return to the equine athletic activity is the main purpose of its use. The association of PRP and stem cells is currently increasingly used and several bone, ligament and tendinous lesions find in this therapeutic form an efficient alternative in the regeneration of such tissues. In our study, we evaluated the in vitro culture of mesenchymal stem cells obtained from the adipose tissue of horses in association with PRP, in order to observe the influence of this on cell proliferation and we found the following results

MEMBROS DA BANCA:
Presidente - 2181699 - PAULO DE TARSO LANDGRAF BOTTEON
Interno - 387386 - MARTA FERNANDA ALBUQUERQUE DA SILVA
Externo à Instituição - DANIEL AUGUSTO BARROSO LESSA - UFF