Banca de DEFESA: MARIANA CORREIA OLIVEIRA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : MARIANA CORREIA OLIVEIRA
DATE: 17/12/2020
TIME: 09:00
LOCAL: Biblioteca Central da UFRRJ
TITLE:

Anatomopathological and immunohistochemical diagnosis of neoplasms in farm animals, diagnosed at the Pathological Anatomy Sector of UFRRJ, from 1947 to 2019.

KEY WORDS:

Tumors, diagnosis, herd, farm, buffalo, buffalo diseases, neoplasms, cattle, cytokeratin, immunohistochemistry, mesothelioma, electromagnetic transmission microscopy

PAGES: 141
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Patologia Animal
SPECIALTY: Anatomia Patologia Animal
SUMMARY:

The study of neoplasms in farm animals is extremely important, since animal health is considered a limiting factor in the development of animal production. The objective of this work was to study the neoplasms of cattle, sheep, goats, buffaloes, horses, pigs, rabbits and chickens, diagnosed in the Pathological Anatomy Sector of the Federal Rural University of Rio de Janeiro (SAP / UFRRJ), during a period of 72 years of extension services (1947-2019). The tools used for the confirmation and / or conclusion of the diagnoses included clinical signs, macroscopic description of the lesions and histological exams. In some cases, immunohistochemistry was used as an aid and electron microscopy was used in a diagnosis. This study was divided into three chapters: chapter I describes 839 neoplasms in farm animals, according to the anatomopathological diagnosis related to the affected species and the organic system in which the neoplasia developed. The cattle showed the highest number of diagnoses (41.2%), followed by the hens (36.7%), horses (13%), swine (2.9%), rabbits (2.9%), buffaloes (1, 6%), goats (1.6%) and sheep (0.1%). Squamous cell carcinoma was the main cancer diagnosed in cattle (37.6%), in goats (69.2%); in the sheep species, only one case of neoplasia was diagnosed during the study period. Neoplasms of the hematopoietic system stood out in chickens, due to the high frequency of avian leukosis (lymphoid and myeloid) with 74.7%. Equine sarcoid and melanoma were the two most common neoplasms in horses, with 23.8% and 14.7%, respectively. Melanoma was also highlighted in swine with 58.3% and the integumentary system showed the highest frequency of tumors in rabbits (37.7%). In chapter II, the descriptions of 12 diagnoses of neoplasms of buffaloes were deepened, based on samples from the state of Pará. Of these 12, four cases were diagnosed as lymphoma, two as skin squamous cell carcinoma, two pheochromocytomas, both metastatic to abdominal organs. and one case of each of the following neoplasms: neurofibroma in the skin, uterine leiomyoma, ovarian tecoma (the latter two in the same female), and osteochondrosarcoma in the unilateral nasal cavity. Chapter III deals with a series of cases of malignant epithelioid mesotheliomas, of the tubulopapillary type, in four Red Sindi cows aged 15 to 21 years, from the same herd. In addition to clinical signs, macro and microscopy typical of mesothelioma, neoplastic cells showed strong and diffuse cytoplasmic immunostaining for pan-cytokeratin, but were negative for cytokeratin 7 and vimentin. Ultrastructurally, neoplastic cells had delicate microvilli and narrow, anchoring junctions.

BANKING MEMBERS:
Interno - 2929022 - SAULO ANDRADE CALDAS
Interna - 6387102 - MARILENE DE FARIAS BRITO QUEIROZ
Interna - 3247698 - TICIANA DO NASCIMENTO FRANCA
Interna - 2606155 - VIVIAN DE ASSUNCAO NOGUEIRA CARVALHO
Externo à Instituição - MICHEL JOSÉ SALES ABDALLA HELAYEL - UFF
Externo à Instituição - PEDRO SOARES BEZERRA JUNIOR - UFPA
Externo à Instituição - TIAGO DA CUNHA PEIXOTO - UFBA