IRRITATIVE LIMIAR OF Ctenocephalides felis felis FOR DEFLAGRATION OF CLINICAL SIGNS IN FELINES WITH DERMATITIS ALLERGIC TO FLEAS
Flea, DAPE, Allergy
Allergic dermatopathies are among the main diseases affecting dogs and cats, and are frequent causes of demand for veterinary services, since they occur with intense pruritus, leading to a decrease in the quality of life of the animals and consequently of the tutors. Flea bite allergic dermatitis (DAPE) affects dogs and cats, a disease often diagnosed at sites with ectoparasite infestations. In cats the lesions occur mainly in the head region, and although it is very prevalent, there are few studies on the disease in this species. The diagnosis of DAPE is clinical and therapeutic, and there is no specific examination that detects the disease. In patients with characteristic lesions, although there is no evidence of fleas or signs of infestation at the time of the consultation, the treatment of the animal and the environment is chosen. It is reported in the literature and widely reported among veterinarians that once the patient has the disease, a single flea bite is enough to trigger the allergic stimulus and the onset of lesions. Therefore the control of ectoparasites must be intense and the total elimination of fleas is recommended. It is known, however, that most of the ectoparasiticides available on the market have systemic action, although many are applied topically, ie the fleas have to prick the host, and then they absorb the drug and are eliminated. Such drugs are effective in controlling the disease and in preventing injury in cats with DAPE, which leads us to believe that the claim that only one flea is necessary to trigger the allergic stimulus is false. With this work we hope to show that the flea bite is not capable of causing cat lesions with DAPE, in order to improve the diagnostic approach of the disease, correlating the clinical signs with the presence of a considerable number of fleas. In addition, we aim to allow greater options in the control of the disease. During the experimental phase two groups will be used, one sick group and another control group. The first group will consist of 12 cats previously diagnosed with DAPE, while the second group will consist of 12 healthy animals. The animals will be isolated and free of infestations, with only cats being selected without skin lesions. Both groups will be infested with increasing numbers of fleas at one-month intervals until clinical signs appear. The fleas will be placed on the flanks of the cats for 10 minutes, and then will be dissected to ensure that there was feed. Cats will be observed for 7 days after each infestation, and the appearance and evolution of the five main clinical signs of the disease will be evaluated: pruritus, alopecia, erythema, papules and crusts. The data obtained will be submitted to statistical analysis, and it is expected to show that a flea bite is not able to trigger the allergic stimulus in cats with DAPE.