Efficacy of Afoxolaner in the clinical management of furuncular myiasis caused by Dermatobia hominis fly (Diptera: Cuterebridae) in naturally infested dogs
isoxazoline; botfly; ectoparasite; maggot; furunculosis
Dermatobia hominis is a botfly that causes furuncular myiasis in several species of wild and domestic animals, including dogs. Lesions can cause local inflammation, serosanguinous exudate formation, pain and pruritus. Recently, the isoxazolines have been used in treatment of this parasitosis for its practicality and hight effectiveness. The aim of this study was to evaluate the effectiveness of afoxolaner in the treatment of dogs naturally infested with D. hominis larvae. Eleven dogs naturally infested with D. hominis were enrolled and diagnosed by observation of skin nodules and visualization of larval motility and treated with single oral dose of afoxolaner, all living in the state of Rio de Janeiro, Brazil. Twe nty-four hours post treatment all larvae were found dead but were necessary to perform manual removal. Afoxolaner were effective as larvicidal treatment for dogs with furuncular myiasis, reducing discomfort and promoted healing of lesions.