Banca de DEFESA: CARLOS EDUARDO MARQUES DE OLIVEIRA FILHO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : CARLOS EDUARDO MARQUES DE OLIVEIRA FILHO
DATE: 23/12/2025
TIME: 14:00
LOCAL: Sala Prof. Laerte Grisi - Grisius LQEPV (Bloco G do Anexo I do IV)
TITLE:

Evaluation of the Efficacy of Fluralaner Against Rhipicephalus linnaei in Artificially Infested Dogs

KEY WORDS:

parasite control, isoxazoline, tick

PAGES: 52
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

The tick Rhipicephalus linnaei is an ectoparasite of medical and veterinary importance, widely distributed in tropical regions, associated with clinical damage in dogs and the transmission of pathogens. Although the efficacy of fluralaner has already been demonstrated for other tick species, there are still few studies evaluating its performance against R. linnaei. The present study aimed to evaluate the tickicidal efficacy of fluralaner, administered orally in a single dose, in the control of R. linnaei in artificially infested dogs. Twenty clinically healthy Beagle dogs were used, of which 16 were selected after ranking and randomly distributed into a treated group (n = 8) and a negative control group (n = 8). The animals were artificially infested with adult R. linnaei ticks and subjected to live and fixed tick counts on days D+2, D+7, D+14, D+21, D+28, and D+35 after treatment. Tick control efficacy was calculated based on the comparison between the arithmetic and geometric means of the groups, as recommended by the World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.). Fluralaner promoted complete elimination of ticks already at the first evaluation (D+2), with 100% efficacy, maintaining sustained control throughout the experimental period. Arithmetic and geometric efficacies remained above 99% between D+2 and D+35, with statistically significant differences compared to the control group (p < 0.001). No treatment-related adverse effects were observed during the study. It is concluded that fluralaner, administered in a single oral dose, has high tickicidal efficacy against R. linnaei in artificially infested dogs.

COMMITTEE MEMBERS:
Presidente - 1173660 - FABIO BARBOUR SCOTT
Interna - ***.630.647-** - BARBARA RAUTA DE AVELAR - UFJF
Interna - ***.192.427-** - DEBORA AZEVEDO BORGES - UFRRJ
Interna - 2929889 - THAIS RIBEIRO CORREIA AZEVEDO
Externo à Instituição - GEORGE REGO ALBUQUERQUE - UESC
Externa à Instituição - LILIAN CRISTINA DE SOUSA OLIVEIRA BATISTA CIRNE - CESVA