The importance of natural coccidia infection (Apicomplexa: Toxoplasmatinae) in pet animals: clinical and ophthalmic manifestations in dogs seroreactive to Neospora caninum Dubey et al., 1988 attended at Animal Health Center in the Mountainous Region of the State of Rio de Janeiro
Dogs; coccídian; Neospora caninum;
Since when described in dogs as a neurological and muscular disease similar to toxoplasmosis and, after taht, classified as a new coccidiosis of the genus Neospora, Neospora caninum species, the study of neosporosis advanced considerably. In the first decade post description, was described as a disease that causes encephalitis and paresis of hind limbs in dogs and that could be fatal. However, from the identification of the main cause of abortion in dairy cattle and of beef cow in several countries, causing serious economic losses, the clinical and epidemiological investigations began to focus on the disease in production animals. Even though it is a disease that may be fatal in dogs, it has been in the background in scientific research. This study aims to bring a general clinical and regional epidemiological view regarding the disease in dogs, its observed clinical signs, as well as the ophthalmic findings in dogs, when seroreagentes to N. caninum. For that, we reviewed the medical records of 201 dogs, examined at an animal health unit located in the city of Teresópolis, which receives patients from the whole mountain region of the state of Rio de Janeiro, during the period from July 2014 to June 2017. Animals were included when, for some reason, complained of and symptoms suspected of neurological and or neuromuscular disease, related to N. caninum infection. As an exclusion criterion, those from whom other diseases were diagnosed that justified their clinical signs. In addition to the hemogram, the ELISA results were evaluated, being considered positive those animals that presented IgG and or IgM titers greater than or equal to 1/50, being this the cut-off point used in the study. Based on this cross-sectional study, the following results were obtained: the highest percentage found in the mountain region was 39.80% of seroreagent animals for N. caninum. The majority of the records referred to non-breed animals, where the percentage of seroreagents was higher (p = 0.0461) than in animals with defined breed. Regardless of the animal race examined, the most frequent clinical signs were muscle atrophy (p = 0.0311), and clinical signs of neurological impairment (p <0.0001) in N. caninum seroreagent dogs. Among the seroreagent patients the most frequent ocular signs were: retinitis, chorioretinitis, optic neuritis and retinal detachment. In the anterior segmento f the eyeball: miosis (p <0.0001), high intraocular pressure (p = 0.0001), cataract (p = 0.0369) and lens luxation (p = 0.0272). Thus, it concludes that castration can still be considered as a protection factor for the congenital infection of canine neosporosis. The age between one and ≤ 7 years is a risk factor and includes the largest number of seroreagent animals to N. caninum (p = 0.0444). Because they were within normal limits, hematological values were not considered as determinants of the natural infection by N. caninum according do the records of dogs examined in Teresópolis, unless there was concomitant infection of Ehrlichia canis.