Banca de QUALIFICAÇÃO: DAYANE CAICÓ COLLARES ARAUJO

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE : DAYANE CAICÓ COLLARES ARAUJO
DATA : 02/06/2020
HORA: 09:00
LOCAL: Laboratório de Quimioterapia Experimental em Parasitologia Veterinária (On line)
TÍTULO:

Evaluation of megavoltage radiotherapy in the treatment of synonasal neoplasms in dogs

PALAVRAS-CHAVES:

Keywords: neoplasms, nasal cavity, radiation.

PÁGINAS: 50
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
ESPECIALIDADE: Clínica Veterinária
RESUMO:

The increase in life expectancy of dogs and cats has led to a higher incidence of chronic diseases, including neoplasms. Sinonasal neoplasms are more frequent in dogs than in cats and represent about 1% of all neoplasms. Factors related to carcinogenesis may be related to mutation of the p53 protein and environmental factors, such as pollution. The objective of the study was to evaluate the therapeutic response of canine sinonasal neoplasms to megavoltage radiotherapy and, consequently, its influence on the survival and quality of life of these animals. For this, 24 dogs diagnosed by means of histopathological and / or cytological examination, with sinonasal neoplasms, were used from November 2016 to December 2019. The average age of patients was 11 years and the highest incidence of carcinoma diagnosis (19/24), of these, 13 animals were males and 11 females. The most frequent clinical signs were sneezing, nasal noise and nasal bleeding. The dogs were treated with radiotherapy in total doses from 42 to 54 Gy (for carcinomas) to 45 Gy (for sarcomas) in 15 fractions of 2.8 Gy to 3.0 Gy, respectively. Patients were evaluated clinically and tumor staging followed the criteria of Adams et al. (1998) according to the cranial tomography. Side effects during and after radiotherapy were classified according to a score established by the Veterinary Radiation Therapy Oncology Group, with a score ranging from 0 to 3. Survival assessment was related to the stage of the tumor and counted in days.

MEMBROS DA BANCA:
Externo ao Programa - 3120060 - ALEXANDRE JOSE RODRIGUES BENDAS
Externo ao Programa - 3151827 - BRUNO RICARDO SOARES ALBERIGI DA SILVA
Externo ao Programa - 2318733 - DANIEL DE ALMEIDA BALTHAZAR
Externo ao Programa - 4563410 - JULIO ISRAEL FERNANDES