Banca de QUALIFICAÇÃO: ISABELLE ABDO DE OLIVEIRA TORRES

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : ISABELLE ABDO DE OLIVEIRA TORRES
DATE: 07/10/2024
TIME: 13:30
LOCAL: meet
TITLE:

Pharmaceutical form based on commercial essential oils for the treatment of incisional skin wounds in mice

KEY WORDS:

herbal medicine, wound and essential oil.

PAGES: 19
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

Skin lesions are characterized by anatomical rupture that compromises functional integrity. The epidermis is the first protective barrier in vertebrate animals. The use of medicinal plants in veterinary medicine has increased, since several drugs used in healing therapy can cause resistance. The objective was to evaluate the healing action of ointments based on essential oils of Lavandula angustifolia 5%, Cymbopogon nardus 5% and the mixture of L. angustifolia with C. nardus at 2% and 5%, in incisional wounds in mice. The oils were obtained commercially and the ointments were produced at concentrations of 2% and 5%. The animals were divided into groups G1-control, G2-treated with ointment based on L. angustifolia 5%, G3-treated with ointment based on C. nardus 5%, G4-treated with ointment based on L. angustifolia and C. nardus 2% and G4b-treated with ointment based on L. angustifolia and C. nardus 5%. Injuries were performed surgically, and treatments were performed daily; on the 21st day, the animals were euthanized, and fragments were collected for histopathology. The group treated with ointment based on L. angustifolia and C. nardus 5% obtained a longer wound reduction time and healing quality than the other treatments, as demonstrated by macroscopic monitoring by caliper measurement and histopathology, since the recruitment of mononuclear cells, first defense cells was moderate, vascular proliferation moderate and collagen fibers organized and of adequate intensity.

COMMITTEE MEMBERS:
Interna - 1722406 - SHANA DE MATTOS DE OLIVEIRA COELHO
Interna - 1700427 - YARA PELUSO CID
Externa à Instituição - ERICA CRISTINA ROCHA ROIER
Externa à Instituição - LEILANE MARIA BARCELLOS NEPOMUCENO