Recurrent pyoderma in atopic dogs as a source of infection for humans
Canine atopic dermatitis, recurrent pyoderma, methicillin-resistant Staphylococcus pseudintermedius, antimicrobial resistance, zoonosis
Recurrent pyodermatitis in dogs with atopic dermatitis poses significant health challenges, including the emergence of antibiotic-resistant bacterial strains such as methicillin-resistant Staphylococcus pseudintermedius (MRSP). This study aimed to identify resistant and multi-resistant bacterial strains in dogs diagnosed with atopic dermatitis and pyodermatitis treated at the Federal Rural University of Rio de Janeiro Veterinary Hospital. A total of 107 canine samples were analyzed through phenotypic and genotypic approaches, including antibiograms and molecular characterization of resistance genes (mecA). Results indicated a high prevalence of S. pseudintermedius among isolates, with 36% carrying the mecA gene, conferring methicillin resistance. Multidrug resistance was observed in 33% of isolates, highlighting an alarming level of resistance to commonly used antibiotics such as penicillin and cephalexin. The findings underscore the importance of rational antibiotic use in veterinary medicine to mitigate the public health risks associated with zoonotic transmission of resistant bacteria. Educational initiatives targeting veterinarians are recommended to promote better antibiotic stewardship and awareness.