Banca de DEFESA: STEPHANIE CARDOSO DA SILVA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : STEPHANIE CARDOSO DA SILVA
DATE: 24/02/2025
TIME: 14:00
LOCAL: Laboratório de Quimioterapia Experimental em Parasitologia Veterinária (LQEPV)
TITLE:

GASTROINTESTINAL ENDPARASITOSES IN DOGS DIAGNOSED WITH NEOPLASMS IN RIO DE JANEIRO

KEY WORDS:

Canine; immunosuppression; oncology; parasites.

PAGES: 50
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUBÁREA: Clínica e Cirurgia Animal
SPECIALTY: Clínica Veterinária
SUMMARY:

Changes in society and the urban environment have brought dogs and humans closer together, fostering an affectionate relationship that contributes to the animals' longevity. As a result, there has been an increase in the diagnosis of chronic and malignant diseases such as cancer. Despite advances in veterinary medicine, diseases caused by intestinal parasites, which are still neglected, are one of the main causes of morbidity in dogs, with symptoms such as vomiting, diarrhoea, anorexia and anaemia. Healthy dogs can be asymptomatic, but cancer patients have a compromised immune system, either due to the disease or treatment, which favours the development of clinical signs that affect well-being and can interrupt treatment. Although the rate of endoparasite infection and the incidence of cancer in dogs is high, coproparasitological investigation before treatment is still little practised, and there is no data in the literature on the occurrence of these infections in these patients. The aim of this study was to assess endoparasitoses in dogs with neoplasms and correlate them with the oncological disease (cytological/histopathological type), comparing them with animals free of neoplasms and immunosuppressive diseases. The dogs were divided into two groups: group I (with neoplasms) and group II (free of neoplasms), with 80 individuals in each. For the coproparasitological assessment, the owners were asked to collect faeces from the dogs in jars with MIF for three consecutive days. The material was analysed using three methods: centrifugation-flotation, centrifugation-sedimentation and the Faust technique. The results of the tests and the clinical information obtained from the medical records were tabulated for later analysis. In dogs with cancer, parasites of the genera Ancylostoma spp. and Trichuris spp. were found, while in dogs without neoplasms, Ancylostoma spp., Trichuris spp., Toxocara spp., Giardia sp. and Cystoisospora spp. were observed. The group of patients with neoplasms had the highest number of positive results in the coproparasitological tests, with the dogs diagnosed with skin tumours being the most affected. The age of the positive animals ranged from 4 to 14 years, and males (7/26) had more positive results than females (4/57). The most frequent histological type in the positive males was mastocytoma (4/7), of which 3 had multiple tumours with different histological types. In the females, the tumours varied between mammary neoplasms, ovarian tumours and skin neoplasms, and 2 had more than one histological type. It is concluded that coproparasitological investigations should be carried out during the screening and staging examinations of all dogs with neoplasms, and that dogs with multiple neoplasms appear to be more susceptible to endoparasite infections.

COMMITTEE MEMBERS:
Presidente - 4563410 - JULIO ISRAEL FERNANDES
Externo ao Programa - 1120060 - ALEXANDRE JOSE RODRIGUES BENDAS - UFRRJExterno ao Programa - 1151827 - BRUNO RICARDO SOARES ALBERIGI DA SILVA - UFRRJExterno à Instituição - CAROLINA FRANCHI JOÃO - UFU
Externa à Instituição - LILIAN BATISTA DA SILVA - CESVA